If you’re like me, you might be wondering why it takes 6 clicks to order an aspirin (a first-line treatment for heart attack) or 47 clicks to document a physical exam for back pain (observed in 1 in 2 Americans). You might also be wondering how emergency medicine physicians tolerate such burdensome workflows every shift.

Generative artificial intelligence (AI) and specifically, large language models (LLMs), are transforming user experience in healthcare and life sciences. In a rather short period of time, LLMs have demonstrated striking competence with biomedical data retrieval and information synthesis. Conversational interfaces powered by LLMs are facilitating biomedical data access and information synthesis via natural language, catalyzing a new paradigm in biomedical human-computer interaction.