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Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq

  • Article
  • Dec 19, 2021
  • #Biology
www.biorxiv.org
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bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

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Andy Matuschak @andy_matuschak ยท Jan 9, 2022
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Quite breathtaking paper: [link] Computationally identifying transcriptional phenotypes by using CRISPR interference to knockdown genes, then sequencing millions of cells (!) to correlate the varying perturbations with transcription effects.
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