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Disuse-induced skeletal muscle atrophy in disease and nondisease states in humans: mechanisms, prevention, and recovery strategies - PubMed

  • Paper
  • Apr 7, 2022
  • #Health #Medicine
Everson Nunes
@nunesea
(Author)
Tanner Stokes
@tjstokes5
(Author)
James Mckendry, Ph.D.
@james_mckendry
(Author)
Brad Currier
@brad_currier
(Author)
pubmed.ncbi.nlm.nih.gov
Read on pubmed.ncbi.nlm.nih.gov
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Decreased skeletal muscle contractile activity (disuse) or unloading leads to muscle mass loss, also known as muscle atrophy. The balance between muscle protein synthesis (MPS) and... Show More

Decreased skeletal muscle contractile activity (disuse) or unloading leads to muscle mass loss, also known as muscle atrophy. The balance between muscle protein synthesis (MPS) and muscle protein breakdown (MPB) is the primary determinant of skeletal muscle mass. A reduced mechanical load on skeleta …

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Stuart Phillips @mackinprof · Apr 28, 2022
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Outstanding work via @nunesea @tjstokes5 @james_mckendry & @brad_currier Thanks to @AJPCellPhys for the venue!
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